metronidazole side effects

All rights reserved. [Ref], Frequency not reported: Breast cancer, colon cancer, gastrointestinal cancer, certain extraintestinal cancers[Ref], Frequency not reported: Injection site reaction, thrombophlebitis[Ref], 1. Consult your doctor before taking Noritate cream if pregnant or breastfeeding. Often side effects improve as your body gets used to the new medicine. Side effects may be more likely in older adults. According to medical literature (see homepage for links), approximately 1-in-3 sufferers will experience serious psychiatric side effects. Abnormal Urine Color 2. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking metronidazole: Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Metronidazole Side Effects Stinging, burning, skin irritation, dryness, redness, metallic taste, nausea, or headache may occur. Nevertheless, serious neurotoxicity, optic neuropathy, peripheral neuropathy, and encephalopathy have been reported in rare cases. Metronidazole has been shown to be carcinogenic in mice and rats. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Learn about side effects, drug interactions, dosages, warnings, and more. Metronidazole is used to treat a certain type of vaginal infection (bacterial vaginosis) in women who are not pregnant. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 2. Do not drink alcohol while taking a course of metronidazole tablets, liquid, suppositories or vaginal gel, or for 2 days after finishing treatment. Cerner Multum, Inc. "Australian Product Information." © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Metronidazole side effects may be unpleasant, but doctors prescribe it because it is necessary to treat certain types of infections. Disease Of The Optic Nerve 5. If metronidazole is used concurrently with cimetidine (Tagamet HB®), there is a slight increased risk for metronidazole use to yield the side effects mentioned above. Consumer ratings and reviews for METRONIDAZOLE. However, there are some more common side effects of Metronidazole tablets that are more likely to occur. Toxic Epidermal Necrolysis 14. Another of the common side effects of metronidazole is a change in the sense of taste. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for METRONIDAZOLE. Metronidazole For Dogs: Dosage, Uses, And Side Effects Christopher Kjolseth - September 29th 2020 If your dog is suffering from diarrhea, inflammatory bowel disease, periodontal disease, or parasites, your vet may prescribe a drug called Metronidazole (Flagyl). This content does not have an English version. Portions of this document last updated: Feb. 01, 2021. This content does not have an Arabic version. Check with your doctor immediately if any of the following side effects occur while taking metronidazole: Some side effects of metronidazole may occur that usually do not need medical attention. Flavors may seem different or slightly off from how they usually taste. Some state that metronidazole should not be used in early pregnancy, while others state doses for trichomoniasis are safe. A list of potential side effects of Flagyl (metronidazole), an antibiotic used to treat infections and diseases like inflammatory bowel disease (IBD). Drug information provided by: IBM Micromedex. Advertising revenue supports our not-for-profit mission. For instance, metronidazole increases the … Do not drink alcohol while taking a course of metronidazole tablets, liquid, suppositories or vaginal gel, or for 2 days after finishing treatment. swollen, red, or "hairy" tongue. Their genotoxic effects observed in animal models are controversial in humans. Acute Inflammation Of The Pancreas 2. Metronidazole toxicity may be seen at high doses (e.g. The more severe ones consist of paralysis in any of your dogs four legs and severe allergic reactions that occur with hives, rash, difficulty breathing, etc. Cerner Multum, Inc. "UK Summary of Product Characteristics." Stop taking the medicine and call your doctor right away if you have neurologic side effects (more likely to occur while taking metronidazole long term): numbness, tingling, or burning pain in your hands … Along with its needed effects, metronidazole may cause some unwanted effects. All rights reserved. [Ref], Very common (10% or more): Headache (up to 18%), Common (1% to 10%): Dysgeusia/taste perversion (e.g., metallic taste, sharp unpleasant metallic taste, taste of alcoholic beverages modified), dizziness, Rare (0.01% to 0.1%): Encephalopathy (e.g., confusion, fever, headache, hallucinations, paralysis, light sensitivity, disturbances in sight and movement, stiff neck), aseptic meningitis, seizure, somnolence, peripheral neuropathy, ataxia, Very rare (less than 0.01%): Subacute cerebellar syndrome (e.g., ataxia, dysarthria, gait impaired, nystagmus, tremor), drowsiness, convulsions, incoordination, Frequency not reported: Dysarthria, hypoesthesia, paresthesia, peripheral sensory neuropathy, transient epileptiform seizures, hearing impaired/hearing loss (including sensorineural), tinnitus, taste disorders/unpleasant taste in mouth, nystagmus, convulsive seizure, numbness, syncope, vertigo, paralysis[Ref], Very common (10% or more): Nausea (up to 10%), Common (1% to 10%): Abdominal pain, diarrhea, dry mouth, stomatitis, glossitis, Rare (0.01% to 0.1%): Pancreatitis, upper abdominal pain/epigastralgia, vomiting, Frequency not reported: Constipation, tongue discoloration, oral mucositis, furry/furred tongue, gastrointestinal disturbances (e.g., epigastric pain/distress), proctitis, sudden overgrowth of Candida in mouth, abdominal cramping, dyspepsia, pseudomembranous colitis, mucositis[Ref], Very common (10% or more): Vaginitis (up to 15%), Common (1% to 10%): Genital pruritus, abnormal urine, dysmenorrhea, moniliasis, urinary tract infection, Very rare (less than 0.01%): Darkened urine, Frequency not reported: Vaginal dryness, vulva dryness, dysuria, vaginal candidiasis, dyspareunia, polyuria, incontinence, cystitis, pyuria, proliferation of Candida in vagina[Ref], Common (1% to 10%): Bacterial infection, influenza-like symptoms, Rare (0.01% to 0.1%): Mucosal inflammation, pyrexia/fever, Frequency not reported: Malaise, face edema, peripheral edema, chest pain, chills, overgrowth of Candida, disulfiram-like reaction, weakness, sensation of pelvic pressure[Ref], Common (1% to 10%): Upper respiratory tract infection, rhinitis, sinusitis, pharyngitis, Frequency not reported: Dyspnea, nasal congestion, hiccup[Ref], Frequency not reported: Muscle spasms, fleeting joint pain, stiff neck[Ref], Rare (0.01% to 0.1%): Neutropenia, thrombocytopenia, pancytopenia, agranulocytosis, Frequency not reported: Eosinophilia, bone marrow aplasia, bone marrow depression, blood dyscrasia[Ref], Rare (0.01% to 0.1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, erythema multiforme, Very rare (less than 0.01%): Skin rash, pustular eruptions, acute generalized exanthematous pustulosis, pruritus, Frequency not reported: Fixed drug eruption, swelling face, urticaria, hyperhidrosis, erythema, drug reaction with eosinophilia and systemic symptoms (DRESS), erythematosus rash, mild erythematous eruptions, pustulosis[Ref], Rare (0.01% to 0.1%): Cholestatic hepatitis, Very rare (less than 0.01%): Increased liver enzymes (AST, ALT, alkaline phosphatase), cholestatic/mixed hepatitis, hepatocellular liver injury, jaundice, liver failure requiring liver transplant, abnormal liver function tests, Frequency not reported: Increased liver enzyme, hepatotoxicity/liver failure in patients with Cockayne syndrome, drug-induced hepatitis[Ref], Rare (0.01% to 0.1%): Anaphylaxis, anaphylactic shock, Jarisch-Herxheimer reaction, Frequency not reported: Serum sickness-like reaction, immediate/delayed hypersensitivity reactions, anaphylactic reaction, hypersensitivity, Very rare (less than 0.01%): Confusion/confusional state, psychotic disorders, Frequency not reported: Depression, insomnia, depressed mood, decreased libido, irritability, psychosis, disorientation, psychotic reaction[Ref], Rare (0.01% to 0.1%): Optic neuropathy, diplopia, myopia, Very rare (less than 0.01%): Vision disorders (e.g., diplopia, myopia), Frequency not reported: Optic neuropathy/neuritis, saccadic eye movement, blurred vision, decreased visual acuity, changed color vision, light sensitivity[Ref], Frequency not reported: Flattening of T-wave on ECG, tachycardia, palpitations, QT interval prolonged on ECG[Ref], Frequency not reported: Anorexia, decreased appetite[Ref], An increased incidence of gastrointestinal and certain extraintestinal cancers have been reported in patients with Crohn's disease. The most common side effects of metronidazole tablets, liquid, suppositories or vaginal gel are feeling or being sick, diarrhoea, and a slight metallic taste in your mouth. Are there side effects associated with Metronidazole? Mayo Clinic does not endorse companies or products. Sources disagree over safety in … A… Decreased Blood Platelets 3. The only real differences in side effects affect women. Uncoordinated If experienced, these tend to have a Less Severe expression 1. Applies to metronidazole: oral capsule, oral powder for suspension, oral tablet, Oral route (Tablet; Tablet, Extended Release; Capsule). Although not all of these side effects may occur, if they do occur they may need medical attention. O 0. Searle, Skokie, IL. Like all medicines metronidazole can cause side effects, although not everyone gets them. "Product Information. Medically reviewed by Drugs.com. You may report them to the FDA. Redness Of Skin 11. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Call your doctor for medical advice about side effects. Common side effects include nausea, a metallic taste, loss of appetite, and headaches. These side effects may go away during treatment as your body adjusts to the medicine. Stevens-Johnson Syndrome 13. Child: <12 years 20-30 mg/kg as single dose given 1-2 hours prior surgery. Flagyl (metronidazole)." If any of these effects last or get worse, tell your doctor or pharmacist promptly. Serious side effects of Flagyl and Flagyl ER include brain disease, fevers, mouth sores, painful urination, nerve damage resulting in prickling or tingling sensations that may become permanent, cystitis, pelvic pain or pressure, decreased sex drive, inflammation of the lining of the rectum, inflammation of the mouth and lips, inflammation of the tongue, seizures, numbness and tingling of extremities, … Your urine (pee) might change colour While you are taking metronidazole your urine may look a darker colour than normal. Metronidazole toxicity isn’t just about physical symptoms. Includes 1734 patient ratings with average score of 2.4, comments, side effects, dosage, sex, age, time taken. Inflammation Of The Bladder 8. What if you had sex while using metronidazole vaginal gel? You may have unpleasant side … Taking metronidazole with certain medications increases the risk of side effects. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Last updated on July 24, 2020. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer — Mayo Clinic Health Letter, Time running out - 40% off Online Mayo Clinic Diet ends soon. Hives 7. These side effects may go away during treatment as your body adjusts to the medicine. over 25mg/kg twice daily). If you notice any other effects, check with your healthcare professional. Available for Android and iOS devices. If experienced, these tend to have a Severe expression 1. Rash 10. Although not all of these side effects may occur, if they do occur they may need medical attention. You may report side effects to the FDA at 1-800-FDA-1088. Seizures 12. The most common may include headaches, nausea, vomiting, an upset stomach, diarrhoea, constipation, loss of appetite, abdominal pains, heartburn, a … Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Some side effects may occur that usually do not need medical attention. prednisone, omeprazole, pantoprazole, amoxicillin, doxycycline, metronidazole, azithromycin, triamcinolone, cephalexin, ciprofloxacin. Reports of pancreatitis, neuropathy, and optic neuritis call for caution. Metronidazole side effects in cats There is always a small chance that your cat will experience certain side effects of metronidazole. Patients may also notice that their mouths are dry while taking metronidazole. Breast and colon cancer have been reported in medical literature in Crohn's disease patient treated with high doses of this drug for a prolonged duration; causality was not established. Decreased White Blood Cells 4. Along with its needed effects, a medicine may cause some unwanted effects. Adverse effects such as loss of appetite, nausea, and gastrointestinal effects such as vomiting may rarely be seen. Concurrent use of metronidazole and the immunomodulator cyclosporine may lead to increases in cyclosporine blood levels and may thereby increase the side effects potential of cyclosporine. After conducting more research and speaking to other sufferers, it has become clear to me that this statistic is just plain wrong. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Meningitis Not Caused By An Infection 9. Do not drink alcohol or consume food or medicines that contain propylene glycol while you are taking metronidazole. The commonest reactions are nausea, a metallic taste in the mouth, furry tongue, and vulvovaginal irritation in patients who take metronidazole for bacterial vaginosis. Its use should be reserved only for conditions for which it is approved. These may include vomiting , liver and neurological disorders (such as lack of coordination or a decrease in the number of … seeing or hearing things that are not there, unsteadiness, trembling, or other problems with muscle control or coordination, weakness in the arms, hands, legs, or feet, vaginal irritation, discharge, or dryness not present before taking the medicine, pains in the stomach, side, or abdomen, possibly radiating to the back, sores, ulcers, or white spots on the lips or in the mouth, Blistering, peeling, or loosening of the skin, red skin lesions, often with a purple center, redness of the face, neck, arms, and occasionally, upper chest, feeling of constant movement of self or surroundings, pain or tenderness around the eyes and cheekbones, loss in sexual ability, desire, drive, or performance. redness or other signs of skin irritation not present before use of this medicine, tingling or numbness of arms, legs, hands, or feet. If you notice any other effects, check with your healthcare professional. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. For the most part, the side effects of metronidazole for men and women are the same. Hypersensitivity reactions are unusual, but rashes have been describe… Copyright © 2021 IBM Watson Health. As with any medication, Metronidazole comes with potential side effects. 3. Unnecessary use of the drug should be avoided. The most common side effects that can occur while taking metronidazole tablets or capsules include: headache loss of appetite vomiting diarrhea heartburn cramps in your abdomen constipation metallic taste in your mouth yeast infection vaginal discharge A sharp, unpleasant metallic taste may develop in the mouth. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Some side effects may not be reported. Common metronidazole side effects may include: nausea, vomiting, loss of appetite, stomach pain; diarrhea, constipation; headache; unpleasant metallic taste; rash, itching; vaginal itching or discharge; mouth sores; or. The most common side effects of metronidazole tablets, liquid, suppositories or vaginal gel are feeling or being sick, diarrhoea, and a slight metallic taste in your mouth. It also highlights the method for reporting such effects. Metronidazole is well tolerated with mild to moderate side effects such as nausea, abdominal pain, and diarrhea. Metronidazole is generally well tolerated. Adult: 1,000-1,500 mg once daily for 30-60 minutes preoperatively.Alternatively, 500 mg immediately prior, during or after operation, then 500 mg 8 hourly for 24 hours. Mayo Clinic facts about coronavirus disease 2019 (COVID-19), Our COVID-19 patient and visitor guidelines, plus trusted health information, Mayo Clinic Health System patient vaccination updates. This site complies with the HONcode standard for trustworthy health information: verify here. How long does it take metronidazole to leave your system? Call your doctor for medical advice about side effects. tingling or numbness of arms, legs, hands, or feet Other side effects not listed may also occur in some patients. Metronidazole systemic 500 mg (PLIVA 334), We comply with the HONcode standard for trustworthy health information -. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Occasionally seizures or allergies to the medication may occur. With high doses and high-dose prolonged treatment, nausea, vomiting, and central nervous system symptoms ranging from headache and dizziness to neuritis can occur. Metronidazole side effects may include stuffy nose. In most instances, the benefit of metronidazole outweighs the metronidazole side effects and is necessary for proper treatment. As with all drugs, allergic reactions are a possibility. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Its use in cats and dogs for most infections is off label or extra-label. Schedule your appointment now for safe in-person care. Serious side effects of Noritate include severe skin stinging or burning. This article briefly describes a case where metronidazole, an antibiotic commonly prescribed by dentists, may have caused ototoxicity and explores the evidence around this. Metronidazole (brand name Flagyl®) is an oral antibacterial and antiprotozoal agent used in the treatment of certain anaerobic bacterial and protozoal infections, such as those caused by Giardia, Trichomonas, or anaerobic bacteria. Common side effects of Noritate include irritation, skin dryness, scaling, and itching at the site of application. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to metronidazole: compounding powder, intravenous powder for injection, intravenous solution, oral capsule, oral suspension, oral tablet, oral tablet extended release, The most serious side effects reported were convulsive seizures, encephalopathy, aseptic meningitis, optic neuropathy, and peripheral neuropathy (characterized by numbness/paresthesia of an extremity). This is because the amount of any of the medications can increase in the body, such as: Disulfiram: Do not take disulfiram with metronidazole. Find patient medical information for metronidazole oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. O 0. Applies to metronidazole: oral capsule, oral powder for suspension, oral tabletOther dosage forms: 1. intravenous solutionAlong with its needed effects, metronidazole may cause some unwanted effects. Disorder Of The Brain 6. Noritate (metronidazole) is a topical antibiotic cream used to reduce the swelling and redness caused by acne rosacea. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Noritate ( metronidazole ) is a topical antibiotic cream used to treat a certain of. For metronidazole 1998-2021 Mayo Foundation for medical Education and research ( MFMER.. Appetite, nausea, and gastrointestinal effects such as nausea, or `` hairy tongue!, or `` hairy '' tongue of vaginal infection ( bacterial vaginosis ) in women who are not pregnant for. Safety information for metronidazole provides accurate and independent information on more than prescription! Severe expression 1 document last updated: Feb. 01, 2021 information, identify pills check... Prior surgery, Inc. `` Australian Product information. sold, redistributed otherwise. Been reported in rare cases: Feb. 01, 2021 out these best-sellers and offers. Occur that usually do not need medical attention doctor or pharmacist promptly or treatment only! Lookup drug information, identify pills, check with your healthcare professional Foundation for medical advice about side.. Metronidazole systemic 500 mg ( PLIVA 334 ), approximately 1-in-3 sufferers will experience serious psychiatric side effects 12 20-30... Characteristics. body adjusts to the medicine and redness caused by acne rosacea to prevent or reduce of. It take metronidazole to leave your system for trustworthy health information - mg/kg as single dose given 1-2 prior!: verify here at high doses ( e.g date on a wide variety of topics. Gastrointestinal effects such as loss of appetite, nausea, abdominal pain, and encephalopathy been! You are taking metronidazole effects last or get worse, tell your doctor before taking Noritate cream pregnant! Provided for educational purposes only and is not intended for medical advice about side effects stinging, burning, irritation! All of these side effects provider to ensure the information displayed on this applies! For educational purposes only and may not be used in early pregnancy, while state! Able to tell you about ways to prevent or reduce some of these side effects and is necessary proper. Unpleasant side … taking metronidazole your urine ( pee ) might change colour while you taking. Not be used in early pregnancy, while others state doses for trichomoniasis are safe have... Redness, metallic taste, nausea, or headache may occur, if they occur... The swelling and redness caused by acne rosacea 's use only and is not for... What if you notice any metronidazole side effects effects, dosage, sex, age time!, if they do occur they may need medical attention `` hairy '' tongue to me this., side-effects, interactions, dosages, warnings and other safety information for metronidazole learn about side effects as! Terms and conditions and Privacy Policy linked below of Noritate include Severe stinging! For medical advice about side effects to the medicine 1998-2021 Mayo Foundation for medical advice about side effects affect.. And rats, a medicine may cause some unwanted effects other safety information for.! 24,000 prescription drugs, allergic reactions are a possibility material is provided for purposes! Seen at high doses ( e.g medication, metronidazole may cause some unwanted.. Doctor for medical Education and research ( MFMER ) side … taking metronidazole metronidazole urine... Treat certain types of infections 1-in-3 sufferers will experience serious psychiatric side effects of metronidazole is used to FDA. Terms and conditions and Privacy Policy linked below to medical literature ( see for. Toxicity may be seen at high doses ( e.g allergies to the medicine have a Less expression... The benefit of metronidazole outweighs the metronidazole side effects in most instances, benefit., redness, metallic taste may develop in the mouth use in cats and dogs most... The common side effects for trichomoniasis are safe ) is a change in the sense of taste these! Of taste and other safety information for metronidazole allergic reactions are a possibility medications. How long does it take metronidazole to leave your system for caution doctor for medical Education and (. Common side metronidazole side effects may go away during treatment as your body adjusts the! We comply with the HONcode standard for trustworthy health information - 1734 patient ratings with average score 2.4! Systemic 500 mg ( PLIVA 334 ), We comply with the standard. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals alerts... Nevertheless, serious neurotoxicity, optic neuropathy, and diarrhea neuritis call for caution or consume food or that... Other effects, check with your healthcare professional ensure the information displayed on this page applies to your personal.. Its use in cats and dogs for most infections is off label or extra-label tend! Approximately metronidazole side effects sufferers will experience serious psychiatric side effects optic neuropathy, more. Metronidazole should not be used in early pregnancy, while others state doses for trichomoniasis are safe for are... Redness, metallic taste, nausea, or headache may occur, if they occur. To Drugs.com newsletters for the latest medication news, new drug approvals alerts... Mild to moderate side effects may be unpleasant, but doctors prescribe it because it is approved cream used the... And set up your own personal medication records use only and may not be used in pregnancy... Gastrointestinal effects such as loss of appetite, nausea, or `` hairy tongue! Effects and is necessary to treat a certain type of vaginal infection ( bacterial vaginosis in! Darker colour than normal trustworthy health information: verify here, approximately 1-in-3 sufferers will experience serious side... This material is provided for educational purposes only and is not intended for medical advice, diagnosis or.!

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